Model Generated by GINsim on 19 June 2013 18:53:29 CEST, by removing the following nodes: PKC, FOXO3, ATF2, FRS2, AP1, p14, MDM2, DUSP1, FOS, MTK1, ATM, JNK, SOS, RSK, MYC, CREB, JUN, ELK1, MAP3K1_3, GAB1, SMAD, PTEN, TAOK, p70, PDK1, MAX, TAK1, MSK, SPRY, GADD45, BCL2, PPP2CA, MEK1_2, PLCG, TGFBR Logical model representing MAPK cascades activation following EGFR, FGFR3, TGFBR and DNA damage stimuli. Proliferation, Apoptosis and Growth arrest outputs (in blue) provide a readout of the contributions of the three main MAPK pathways (ERK, p38, JNK) to cell fate decision. Input signals are emphasised in pink, whereas the reference MAPK are emphasised in lila.